| ABSTRACT: |
|
Despite intensified therapeutic efforts, including such newer
approaches as the use of biological response modifiers and multiple
modalities, further increments in rates of cure and long-term remissions
have not come easily, and this has led to new emphasis on disease
prevention. As a result meetings and papers devoted to cancer prevention
have increased exponentially. This is Volume I of a two-volume publication
developed from a symposium of the Division of Agriculture and Food
Chemistry at the 204th National Meeting of the American Chemical Society,
held in Washington, DC, August 23-28, 1992. It covers the many
phytochemicals in fruits and vegetables, their identification, isolation,
purification, chemical, biochemical, biological and pharmacological
properties, and effects on tumor development in experimental animal
systems and on human health when known. There are 34 chapters organized
into seven sections: perspectives, including an overview of the area, and
consideration of micronutrients, effects of phytochemicals on xenobiotic
metabolism and Japanese research; sulfur-containing phytochemicals in
garlic and onions; other sulfur-containing phytochemicals; limonoids and
phthalides; phytochemicals from fruits and vegetables; phytochemicals in
soybeans; and micronutrients. Among the phytochemicals discussed are
alliin, diallyl sulfide and sulfone, vinyldithiins, phenethyl
isothiocyanate, citrus flavonoids, umbelliferous components,
chlorophyllin, ellagic acid, gallotannins, ellagitannins, soybean
saponins, ascorbic acid, beta-carotene, and licorice. There are author,
affiliation and subject indices. (See also CANCERLIT data base abstract
number ICDB/96616418.) |